Researchers from Tel Aviv University and the Shamir Medical Center claim they have successfully reversed the biological aging process in a group of elderly adults.
The simple but possibly earth-shattering solution was to use a form of oxygen therapy to reverse some key indicators of biological aging in the cells – Telomere length and senescent cells accumulation.
What they call Hyperbaric Oxygen Therapy reversed this aging process at the cellular level. Scientists have been studying how to reverse the effects at this level for years and that they are discovering ways to reverse the process will only lead to more and better technologies.
“Until now, interventions such as lifestyle modifications and intense exercise were shown to have some inhibition effect on the expected telomere length shortening,” said Dr Amir Hadanny, co-author of the study.
“The significant improvement of telomere length shown during and after these unique HBOT protocols provides the scientific community with a new foundation of understanding that aging can, indeed, be targeted and reversed at the basic cellular-biological level.”
“However, what is remarkable to note in our study, is that in just three months of therapy, we were able to achieve such significant telomere elongation – at rates far beyond any of the current available interventions or lifestyle modifications.”
From The Independent:
A clinical trial involving 35 adults over the age of 64 sought to understand whether a method called Hyperbaric Oxygen Therapy could prevent the deterioration of these two hallmarks of the aging process.
The subjects were placed in a pressurised chamber and given pure oxygen for 90 minutes a day, five days a week for three months…
…At the end of the trial, the scientists reported that the participants’ telomeres had increased in length by an average of 20 per cent, while their senescent cells had been reduced by up to 37 per cent.
This is the equivalent to how their bodies were at a cellular level 25 years earlier, the researchers reported.
“Since telomere shortening is considered the ‘Holy Grail’ of the biology of aging, many pharmacological and environmental interventions are being extensively explored in the hopes of enabling telomere elongation,” said Shai Efrati, a professor at the Faculty of Medicine and Sagol School of Neuroscience at Tel Aviv University, and co-author of the study….
…During the latest trial in Israel, the participants did not undergo any lifestyle, diet or medication adjustments, which have previously been found to have moderate effects on a person’s biological age.
It is understood that instead the effects were the result of the pressurised chamber inducing a state of hypoxia, or oxygen shortage, which caused the cell regeneration.